From the first discoveries of chloroquine Resochin in 1934 to the development of carbamate and pyrethroid insecticides to partnerships with institutions like the Innovative Vector Control Consortium, Bayer has actively contributed throughout history to the fight against vector-borne diseases.
Timeline: Key Activities and Contributions to Vector-Borne Disease Management
1960s and early 1970s
Developed and introduced carbamate insecticides as important alternatives to DDT during malaria control campaigns during this time. One of these alternatives, bendiocarb is still an important tool for controlling insecticide-resistant malaria vectors today.
Early to mid-1980s
Developed and introduced some of the first pyrethroid insecticides (eg. cyfluthrin and deltamethrin) which would later become critical for use on insecticide-treated mosquito nets.
- Developed dedicated formulations suitable for treating mosquito nets (K-Othrine SC and later K-O Tab)
- Developed specialised water-based formulations of pyrethroids for space-spray application based on FFAST Technology (Aqua K-Othrine and Aqua Reslin Super), reducing dependency on hydrocarbon based diluents.
- Developed new formulations for indoor residual spraying, based on deltamethrin (K-Othrine WG)
- Invested into regulatory defence of bendiocarb to maintain its availability for IRS against malaria vectors; worked in partnership with mosquito net manufacturers to help with technology development to treat fabrics with Bayer's deltamethrin.
- WHOPES recommendations for the Aqua family of space spray insecticides, K-O Tab 1-2-3 (a longer lasting, in-field mosquito net treatment)
- Established agreements with IVCC for development of new insecticides for Public Health and new, more cost-effective formulations of existing compounds
- Achieved WHOPES recommendation for a new, polymer-enhanced formulation of deltamethrin (K-Othrine PolyZone) borne from the collaboration with IVCC
- Invested into production facilities in Africa for manufacture of Ficam and K-Othrine WG for local IRS programs
- Between 2006 and 2015, increased investment into product development for vector control by nearly 5 times
- In late 2015, submitted the first two-way insecticide mixture for IRS for WHOPES evaluation.
- In April 2018, the world’s leading companies in agriculture (BASF, Bayer, Mitsui Chemicals, Sumitomo Chemical and Syngenta) united at the Malaria Summit held at the Commonwealth Headers of Government Meeting (CHOGM) in London.
- The declaration signed formalizes the collaboration between innovators to work together towards continued progress in fighting malaria by reaffirming their commitment to support the research, development and supply of innovative vector control solutions.
- Bayer recognizes that the challenge to eradicate malaria is far too immense and widespread for one entity alone, but that great things can be accomplished when dedicated leaders from industry, academia, the public sector and non-governmental organizations unite in a very strategic manner behind a common goal
- Indeed, many of the world leading companies in agriculture have played a major role in the progress made to eradicate malaria over the last generation. Together the signatories of the declaration represent a wealth of industry know-how and ability, convened and supported by leading and prestigious organizations.
- For Bayer, as a leading company in the fields of healthcare and agriculture, it is both an honor and a responsibility to be a signatory of the declaration.